Synthomycetine (Lepetit) in Typhoid Fever

Synthomycetine, a new Synthetic brand of Chloramphenicol was tried in two cases of typhoid fever culturally positive. The dosage schedule was moderate and no initial loading dosage was used. The effects on the temperature chart was shown below were not dramatic and, in fact, in the second case it took seven days for the temperature to touch normal (probably due to urinary complications). But general constitutional symptoms and signs improved progressively and no complications like vomiting, diarrhcea or sudden circulatory failure